Nikolas
Created page with "Alzheimer disease (AD) is the most common neurodegenerative disease and the cause of 2/3 of all cases of dementia. It’s characterised by progressive loss of neurons, initially cholinergic ones but later others as well, as well as accumulation of intracellular neurofibrillary tangles and extracellular amyloid plaques. == Risk factors == * Old age * Family history * Head trauma * Vascular risk factors * APOE e4 genotype * Down syndrome == Protective factors == * High..."
