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• 13:32, 26 April 2023 Nikolas talk contribs created page 74. Macrolide antibiotics, clindamycin, chloramphenicol, oxazolidinones, streptogramins (Created page with "== Macrolides == === Compounds === * Erythromycin * Clarithromycin * Azithromycin === Mechanism of action === Macrolides bind to the 50S subunit of bacterial ribosomes, inhibiting translocation. This effect is bacteriostatic. === Mechanism of resistance === Resistance is often encoded by a plasmid. It can be mediated by drug efflux, enzymatic inactivation or changing the binding-site of macrolides on the ribosomes. === Pharmacokinetics === Macrolides are orally abso...") Tag: Visual edit