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- 09:13, 23 April 2023 Nikolas talk contribs created page 58. Drug abuse and dependence: general principles, opioids, anti-anxiety and hypnotic drugs, inhalants, ethanol (Created page with "== General principles of drug dependence and abuse == Drug dependence or addiction refers to the state when drug-taking becomes compulsive and starts to take precedence over other needs. There is an excessive craving for the drug. A common feature of dependence-producing drugs is the activation of the dopaminergic “reward” pathway, the mesolimbic pathway. Most dependence-producing drugs produce a rewarding experience, like an elevation of mood or a feeling of euphori...") Tag: Visual edit