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- 14:30, 22 November 2022 Nikolas talk contribs created page 37. Epidemiology and prevention of prion diseases (Created page with "* Prions ** = wrongly folded proteins which are very resistant, especially against heating ** The protein in question is called PrP and is normally in the C isoform (PrPC protein) ** Transformation to the Sc (scrapie) isoform can occur when a PrPC protein comes into contact with a PrPSc isoform of the protein *** It can also occur spontaneously, but that is extremely rare ** The Sc isoform is resistant to proteolysis ** Transmissible per os * Prion diseases = transmissib...") Tag: Visual edit