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- 08:37, 25 January 2023 Nikolas talk contribs created page 15. Effector mechanisms of cell-mediated immune response (Created page with "== Differentiation of <abbr>CD8</abbr>+ T-cells to cytotoxic lymphocytes == Naïve CD8+ need to be activated by an antigen before it can really be cytotoxic and kill other cells. As we know by now, CD8+ T-cells can only recognize antigens when they are presented by a cell through an MHC I molecule. thumb|This figure shows how CD8+ T-cells (CTL-P) are activated to become CTL cells. Naïve CD8+ cells are also called ''cytotoxic lymphocyt...") Tag: Visual edit