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- 13:28, 16 March 2023 Nikolas talk contribs created page 10. Pharmacokinetics: zero and first order elimination kinetics, elimination half-life, volume of distribution, clearance, maintenance dose, loading dose, oral bioavailability (Created page with "== Summary == * If a drug follows first order elimination the rate of its elimination depends on the plasma concentration of the drug ** This is because the mechanisms which eliminate the drug are not saturated ** Almost all drugs follow first order kinetics * If a drug follows zero order elimination the rate of its elimination is constant ** This is because the mechanisms which eliminate the drug are saturated ** Ethanol and salicylates follow zero order kinetics ** Et...") Tag: Visual edit