44. Prostate adenocarcinoma
Organ: Prostate, bladder, surrounding soft tissue
Description:
The prostate is enlarged and the tumor has spread locally into the soft tissue around. The bladder is dilated due to the compression of the urethra (which only happens in late stages). Nearby lymph nodes are enlarged due to metastasis.
On the back of the preparation is one periprostatic vein cut open.
Diagnosis: Prostate adenocarcinoma
Risk factors:
- Old age
- Positive family history
- BRCA mutation
- HPC-1 mutation
Theory:
Metastatic lymph nodes may compress the periprostatic veins, causing thrombosis with possible pulmonary embolism.