Multiple organ dysfunction syndrome
Multiple organ dysfunction syndrome (MODS), also called multiple organ failure (MOF) is defined as the acute insufficiency of 2 or more organ systems, requiring intervention to maintain homeostasis. It has high mortality, and the mortality increases with the amount of failing organ systems. It is mostly seen as an end-stage of sepsis or other severe systemic inflammatory response syndrome like acute pancreatitis.
The SOFA score is used to evaluate organ function to diagnose MOF.