38. Hydatidiform mole
Staining: HE
Organ: Placenta?
Description:
Both abnormal and normal chorionic villi are present, indicating that this is a partial hydatidiform mole.
The abnormal villi show hydropic swelling, making them much larger than normal villi. They also have a loose, myxomatous and oedematous stroma.
Alternatively, it's a complete mole because of lack of foetal elements and the relatively severe atypia.
Diagnosis: Partial or complete hydatidiform mole (my teacher said partial, others apparently say complete)
Risk factor:
- Asian countries
- Women < 20 or > 40
Theory:
Partial hydatidiform moles usually contain some foetal cells but we do not have to recognize those.