14. Urothelial carcinoma of the renal pelvis

Overview

Staining: HE

Organ: Kidney

Description: A tumor with an apparent well-demarcated border can be seen. The tumor has oval structures as the tumor cells grow on papillary structures. The tumor cells shows only mild atypia (pleiomorphism). Mitotic figures are present.

Upon closer examination of the border between the tumor and the healthy kidney parenchyme can we find some invasive foci inside the parenchyme.

Diagnosis: Urothelial carcinoma of the renal pelvis

Risk factors: Smoking

Theory: See the macropreparation.

Papillary structures in the tumour

Mitotic activity in the tumour

The well-demarcated border isn’t so demarcated after all as the tumor invades past it