39. Viral myocarditis

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Overview. Kinda looks like a smiley face. The marked section is the best one to examine.

Staining: HE

Organ: Myocardium

Description:

We can see many sections of myocardium. The myocardium has many focal accumulations of lymphocytes. Some foci of the myocardium contain no cells, and some have an abnormal cloudy/wavy appearance.

Diagnosis: Viral myocarditis

Causes:

  • Coxsackie virus

Theory:

Evidence number 1 for focal cell necrosis

Two findings are characteristic for myocarditis: focal lymphocyte accumulation and focal cell necrosis. We can see two evidences for focal cell necrosis:

  1. Areas where there are no nuclei
  2. Areas that are wavy/cloudy in appearance
Evidence number 2. This is what I mean by wavy/cloudy parts