Glycoprotein IIb/IIIa inhibitors

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Glycoprotein IIb/IIIa inhibitors are antiplatelets. They are mostly used for short-term treatment before and during percutaneous coronary intervention. They are administered by i.v. injection,

Compounds

  • Abciximab
  • Eptifibatide
  • Tirofiban

Mechanism of action

These drugs bind to and inhibit the receptors glycoprotein IIb/IIIa, which prevents platelets from binding to each other and therefore preventing aggregation.