Laryngeal cancer
- A cancer of older men
- 40% of head and neck cancers
- SCC
- Etiology
- Smoking
- Alcohol
- Types
- Supraglottic
- 40% of cases
- Gives late symptoms
- Glottic
- Best prognosis because gives early symptoms (hoarseness)
- Limited lymphatic drainage
- 60% of cases
- Subglottic
- 1% of cases
- Gives late symptoms
- Dyspnoea
- Stridor
- Supraglottic
- Clinical features
- Hoarseness
- Foreign body sensation
- Dyspnoea
- Dysphagia
- Stridor
- Staging
- TNM
- T1 – confined to one part of larynx
- T2 – invades another part of larynx
- T3 – tumor confined to larynx
- T4 – tumor invades outside the larynx
- N1 – single regional ipsilateral lymph node
- N3 – large regional lymph node
- M1 – distant metastasis
- AJCC stage
- 0 – in situ
- I – T1, N0, M0
- II – T2, N0, M0
- III – T3, N0, M0
- IV – T4 OR N1 OR M1
- TNM
- Treatment
- Early – radiotherapy, laser resection
- Late – laryngectomy
- Neck dissection