15. Epidemiology and prevention of breast cancer
- Epidemiology
- Most common cancer in females
- Second most common cause of cancer-death in female
- Etiology
- Age
- High fat intake
- Ethnicity
- Caucasian > black > asian
- Increase oestrogen exposure
- Late menopause
- Early menarche
- Late first pregnancy
- Nulliparity
- Oral contraceptive
- Overweight
- Not breastfeeding
- Radiation
- Physical inactivity
- Familial
- BRCA1 and 2
- Prognosis
- High 5-year survival: 85%
- Much lower in Asian women
- High 5-year survival: 85%
- Prevention
- Screening
- Yearly mammogram after 40
- Clinical breast exam every 3 years after 20
- Breast self exam
- Prevent obesity
- Physical activity
- Screening