45. Nodular melanoma

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Revision as of 21:05, 15 November 2022 by Nikolas (talk | contribs) (Created page with "'''Staining''': HE '''Organ''': Skin '''Description''': Like the name implies the tumor forms a nodule. The tumor cells are highly atypical, bordering on anaplastic. Some of the tumor cells contain melanin. Tumor cells are present in the epidermis as well. '''Diagnosis''': Nodular melanoma '''Causes''': * Sun exposure '''Theory''': The presence of tumor cells in the epidermis is essential to establish the diagnosis of ''primary'' melanoma. If there were no tumor...")
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Staining: HE

Organ: Skin

Description:

Like the name implies the tumor forms a nodule. The tumor cells are highly atypical, bordering on anaplastic. Some of the tumor cells contain melanin.

Tumor cells are present in the epidermis as well.

Diagnosis: Nodular melanoma

Causes:

  • Sun exposure

Theory:

The presence of tumor cells in the epidermis is essential to establish the diagnosis of primary melanoma. If there were no tumor cells there the lesion could have been a melanoma metastasis rather than the primary tumor.

Overview
Tumour cells containing melanin
Severe atypia, or even anaplasia
Tumour cells in the epidermis