User contributions for Nikolas

15:4515:45, 27 April 2024 diff hist +20‎ N Fibrinogen ‎ Redirected page to Fibrin current Tags: New redirect Visual edit
15:4415:44, 27 April 2024 diff hist −1‎ 18. Describe the two pathways involved in the initiation of blood coagulation ‎No edit summary current
15:4315:43, 27 April 2024 diff hist −1,841‎ 18. Describe the two pathways involved in the initiation of blood coagulation ‎No edit summary Tag: Visual edit
15:4215:42, 27 April 2024 diff hist +751‎ Coagulation tests ‎ →‎Summary Tag: Visual edit: Switched
15:2515:25, 27 April 2024 diff hist +5,498‎ N Coagulation tests ‎ Created page with "<section begin="clinical biochemistry" />Several laboratory tests can be used to evaluate the coagulation system. They're used in the evaluation of bleeding disorders. == Summary == {| class="wikitable" !'''Parameter''' !'''Function examined''' !'''Normal range''' !'''Elevated result in''' |- !Prothrombin time |Extrinsic pathway, vitamin K-dependent factors |15 – 20 seconds |Vitamin K deficiency, liver disease |- !INR |Extrinsic pathway, vitamin K-dependent fa..." Tag: Visual edit: Switched
15:2415:24, 27 April 2024 diff hist +639‎ N Fibrin ‎ Created page with "{{:Stub}} <section begin="clinical biochemistry" />'''Fibrin''' is a protein involved in the coagulation cascade. Its inactive form '''fibrinogen''' is converted to fibrin by thrombin in the last steps of the coagulation cascade. Fibrinogen is synthesised in the liver and is an acute phase protein. == Fibrinogen in laboratory medicine == Fibrinogen can be measured in the plasma in the evaluation of disseminated intravascular coagulation (DIC), bleedin..." current Tag: Visual edit: Switched
14:1114:11, 27 April 2024 diff hist +970‎ N 22. Blood coagulation: cellular components (platelets, endothelial cells) and their laboratory analysis. ‎ Created page with "* Vasculopathies – endothelial dysfunction ** Ehlers-Danlos ** Marfan ** Bleeding time prolonged * Thrombocytopathies – plt dysfunction ** Platelet count and volume *** Measured by impedance or light scatter with flow cytometry ** Thrombocytopaenia *** Heparin induced (HIT) **** Immunoassay tests for antibodies (type 2) ** Thrombocytosis *** Inflammation *** Iron deficiency ** Thrombocythaemia *** Myeloproliferative disease ** Thrombocyte dysfunction *** von Willebra..." current Tag: Visual edit

12:3812:38, 11 April 2024 diff hist +37‎ Main Page ‎ →‎Browse pages by subject Tag: Visual edit
12:3512:35, 11 April 2024 diff hist +29‎ N Category:Pathology ‎ Created page with "Category:Pages by subject" current Tag: Visual edit
12:3112:31, 11 April 2024 diff hist 0‎ Phosphate ‎No edit summary current
12:3012:30, 11 April 2024 diff hist +23‎ Hyperphosphataemia ‎No edit summary current
12:2912:29, 11 April 2024 diff hist +32‎ N Hyperphosphataema ‎ Nikolas moved page Hyperphosphataema to Hyperphosphataemia current Tag: New redirect
12:2912:29, 11 April 2024 diff hist 0‎ m Hyperphosphataemia ‎ Nikolas moved page Hyperphosphataema to Hyperphosphataemia
12:2612:26, 11 April 2024 diff hist +23‎ Neuroimaging ‎No edit summary current
12:2312:23, 11 April 2024 diff hist +359‎ Main Page ‎ →‎Browse pages by subject Tag: Visual edit
12:1612:16, 11 April 2024 diff hist +29‎ N Category:Physiology ‎ Created page with "Category:Pages by subject" current Tag: Visual edit

15:1515:15, 9 April 2024 diff hist +631‎ N 21. Laboratory findings in the disorders of iron metabolism. ‎ Created page with "= Iron = {{#lst:Iron|clinical biochemistry}} = Ferritin = {{#lst:Ferritin|clinical biochemistry}} = Transferrin = {{#lst:Transferrin|clinical biochemistry}} == Summary == {| class="wikitable" !'''Disorder''' !'''Serum iron''' !'''Transferrin''' !'''Ferritin''' !'''Soluble transferrin receptor''' !'''Reticulocytes''' |- !'''Iron deficiency anaemia''' |↓ |↑ |↓ |↑ |↓ |- !'''Haemoglobinopathy''' |Normal |Normal |Normal |Normal |Normal |- !'''Anaemia of chronic dis..." current Tag: Visual edit
15:1115:11, 9 April 2024 diff hist +787‎ Transferrin ‎No edit summary current Tag: Visual edit
14:5614:56, 9 April 2024 diff hist +54‎ N Transferrin receptor ‎ Redirected page to Transferrin#Soluble transferrin receptor current Tags: New redirect Visual edit
14:5514:55, 9 April 2024 diff hist +95‎ Ferritin ‎No edit summary current Tag: Visual edit
14:5214:52, 9 April 2024 diff hist +1,605‎ N Ferritin ‎ Created page with "<section begin="clinical biochemistry" />Free iron ions are toxic to the cells, as they create reactive oxygen species through the Fenton reaction. They are therefore stored in a protein called '''ferritin'''. One molecule of ferritin can store up to 4500 iron atoms. Note that the pure protein-only, non-iron-bound protein is called '''apoferritin'''. Ferritin is mostly found in the liver. Ferritin is a positive acute phase protein. == Ferritin in laboratory med..." Tag: Visual edit: Switched
14:2614:26, 9 April 2024 diff hist +2,133‎ N Transferrin ‎ Created page with "<section begin="clinical biochemistry" />'''Transferrin''' is a serum protein whose function is to transport iron in the blood; more specifically, each molecule of transferrin binds two Fe<sup>3+</sup> ions with high affinity. Transferrin binds to transferrin receptors on cells which require iron, after which the transferrin-transferrin receptor complex is endocytosed. The pure protein, non-iron-bound form of transferrin is called '''apoferritin'''. Transferrin is a..." Tag: Visual edit: Switched
14:0514:05, 9 April 2024 diff hist +33‎ N Acute phase proteins ‎ Nikolas moved page Acute phase proteins to Acute phase protein current Tag: New redirect
14:0514:05, 9 April 2024 diff hist 0‎ m Acute phase protein ‎ Nikolas moved page Acute phase proteins to Acute phase protein current
13:5113:51, 9 April 2024 diff hist +444‎ N Iron ‎ Created page with "{{:Stub}} == Serum iron (laboratory medicine) == <section begin="clinical biochemistry" /> * Diurnal variation * 30% Biological variation * Influenced by inflammation, diet * Detected by coupled enzymatic reaction which form coloured complexes -> photometry * Not used to determine iron status, ferritin and transferrin are used instead <section end="clinical biochemistry" /> Category:Laboratory Medicine Category:Biochemistry" current Tag: Visual edit: Switched

18:0018:00, 3 April 2024 diff hist +239‎ N 20. Haemoglobinopathies: disorders of the porphyrin metabolism. ‎ Created page with "= Sickle cell disease = {{#lst:Sickle cell disease|clinical biochemistry}} = Thalassaemia = {{#lst:Thalassaemia|clinical biochemistry}} = Porphyria = {{#lst:Porphyria|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)" current Tag: Visual edit
18:0018:00, 3 April 2024 diff hist +3,476‎ N Porphyria ‎ Created page with "<section begin="clinical biochemistry" />'''Porphyrias''' are genetic diseases where there are defects in one of the enzymes required for porphyria synthesis. Porphyrins are circular molecules which consist of four porphobilinogen molecules. Many proteins contain porphyrins, including haemoglobin, myoglobin, cytochromes, and NO-activated guanylyl cyclase. Porphyrias are rare disorders, but the prevalence varies significantly with geography. Fo..." current Tag: Visual edit: Switched
17:0417:04, 3 April 2024 diff hist +2‎ Thalassaemia ‎No edit summary current
17:0417:04, 3 April 2024 diff hist +158‎ Thalassaemia ‎No edit summary
17:0317:03, 3 April 2024 diff hist +160‎ Sickle cell disease ‎No edit summary current
17:0217:02, 3 April 2024 diff hist +172‎ N 19. Laboratory diagnostic approaches in anaemias. ‎ Created page with "= Anaemia = {{#lst:Anaemia|clinical biochemistry}} = Haemolytic anaemia = {{#lst:Haemolytic anaemia|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)" current Tag: Visual edit
17:0117:01, 3 April 2024 diff hist +160‎ Haemolytic anaemia ‎No edit summary current
17:0117:01, 3 April 2024 diff hist +762‎ Anaemia ‎No edit summary current Tag: Visual edit: Switched
16:5716:57, 3 April 2024 diff hist +303‎ N 18. Laboratory diagnosis of malignant hematologic disorders; complete blood count and flow cytometry ‎ Created page with "For complete blood count, see topic 17. For diagnosis of multiple myeloma, see topic 15. = Flow cytometry = {{#lst:Flow cytometry|clinical biochemistry}} = Bone marrow aspiration and biopsy = {{#lst:Bone marrow aspirate and biopsy|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)" current Tag: Visual edit
16:5616:56, 3 April 2024 diff hist +294‎ Bone marrow aspirate and biopsy ‎No edit summary current Tag: Visual edit
16:5316:53, 3 April 2024 diff hist +1,126‎ N Bone marrow aspirate and biopsy ‎ Created page with "<section begin="clinical biochemistry" />'''Bone marrow aspirate''' and '''bone marrow biopsy''' are two examinations used in the evaluation of the bone marrow, indicated in case of unexplained haemotological disorder (like unexplained anaemia, leukopaenia, etc.) and in the evaluation of leukaemia and lymphoma. Bone marrow aspiration involves aspirating a small part of the liquid bone marrow. This is technically more simple to perform and gives informati..." Tag: Visual edit: Switched

21:5821:58, 27 March 2024 diff hist +144‎ Leukocyte ‎No edit summary Tag: Visual edit
21:5321:53, 27 March 2024 diff hist +959‎ N Blood smear ‎ Created page with "<section begin="clinical biochemistry" />'''Blood smear''', sometimes called '''peripheral blood smear''' (probably to distinguish it from a bone marrow aspirate?) is a Giemsa stained thin film of blood on a glass microscopic slide. It allows morphological examination of blood cells and platelets. It's used in the evaluation of anaemia and leukaemia. In many types of anaemia there is abnormal morphology of the red blood cells, like in sickle cell anaemia, here..." current Tag: Visual edit: Switched
21:3621:36, 27 March 2024 diff hist +133‎ Flow cytometry ‎No edit summary current Tag: Visual edit: Switched
21:2921:29, 27 March 2024 diff hist 0‎ Leukocyte ‎No edit summary Tag: Visual edit
21:2721:27, 27 March 2024 diff hist +89‎ Leukocyte ‎No edit summary Tag: Visual edit
21:2521:25, 27 March 2024 diff hist +337‎ N 17. Laboratory findings in inflammatory disorders ‎ Created page with "= Leukocytes = {{#lst:Leukocyte|clinical biochemistry}} = C-reactive protein = {{#lst:C-reactive protein|clinical biochemistry}} = Procalcitonin = {{#lst:Procalcitonin|clinical biochemistry}} = Erythrocyte sedimentation rate = {{#lst:Erythrocyte sedimentation rate|clinical biochemistry}} Category:Clinical Biochemistry (POTE course)" current Tag: Visual edit
21:2521:25, 27 March 2024 diff hist −4,407‎ 15. Characterize the various leukocytes indicating their origins and functions ‎ Replaced content with "{{#lst:Leukocyte|physiology}} Category:Physiology 1" current Tags: Replaced Visual edit
21:2421:24, 27 March 2024 diff hist +298‎ Leukocyte ‎No edit summary
21:2321:23, 27 March 2024 diff hist +6,194‎ Leukocyte ‎No edit summary Tag: Visual edit: Switched
09:4409:44, 27 March 2024 diff hist +2,307‎ N Erythrocyte sedimentation rate ‎ Created page with "<section begin="clinical biochemistry" />'''Erythrocyte sedimentation rate''' (ESR), also called the '''Westergren method''' (We), is a laboratory measurement of how quickly the erythrocytes in a sample sediment (settle on the bottom of the tube). The ESR increases in response to the acute phase reaction (inflammation), but it takes many days for the ESR to increase following an inflammation, and it takes weeks to normalise. The normal value depends on age and ge..." Tag: Visual edit: Switched
09:2709:27, 27 March 2024 diff hist +23‎ N Leukocytes ‎ Nikolas moved page Leukocytes to Leukocyte current Tag: New redirect
09:2709:27, 27 March 2024 diff hist 0‎ m Leukocyte ‎ Nikolas moved page Leukocytes to Leukocyte
09:2709:27, 27 March 2024 diff hist +11‎ Leukocyte ‎No edit summary Tag: Visual edit
09:2209:22, 27 March 2024 diff hist +34‎ N Acute phase reaction ‎ Redirected page to Acute phase proteins current Tags: New redirect Visual edit

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