All public logs

Combined display of all available logs of greek.doctor. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).

08:36, 9 May 2022 Nikolas talk contribs uploaded File:Haemorrhagic infarct of the lung overview.jpg
08:33, 9 May 2022 Nikolas talk contribs created page 3. Recent infarct of the heart (Created page with "'''Staining:''' HE '''Organ:''' Heart '''Description:''' On the left side of the slide we can see fat cells, belonging to the sub-epicardial fat. Therefore, the endocardium is to the right on the slide. We can see mostly a normal myocardium, however there is a more eosinophilic area under the endocardium. If we zoom in we can see that the cells are more eosinophilic, there are few nuclei visible, and the cross-striation has mostly disappeared in comparison to the othe...") Tag: Visual edit
08:33, 9 May 2022 Nikolas talk contribs created page File:Recent myocardial infarction fibroblasts.jpg
08:33, 9 May 2022 Nikolas talk contribs uploaded File:Recent myocardial infarction fibroblasts.jpg
08:33, 9 May 2022 Nikolas talk contribs created page File:Recent myocardial infarction demarcation zone.jpg
08:33, 9 May 2022 Nikolas talk contribs uploaded File:Recent myocardial infarction demarcation zone.jpg
08:32, 9 May 2022 Nikolas talk contribs created page File:Recent myocardial infarction low magnification.jpg
08:32, 9 May 2022 Nikolas talk contribs uploaded File:Recent myocardial infarction low magnification.jpg
08:31, 9 May 2022 Nikolas talk contribs created page File:Recent myocardial infarction overview.jpg
08:31, 9 May 2022 Nikolas talk contribs uploaded File:Recent myocardial infarction overview.jpg
08:28, 9 May 2022 Nikolas talk contribs created page 2. Apoptosis in a reactive lymph node (follicular hyperplasia) (Created page with "'''Staining:''' HE '''Organ:''' Lymph node '''Description:''' We can see a normal-looking lymph node with several germinal centres. Inside the germinal centres we can see a “starry-sky” pattern. Apoptotic bodies, seen as small round eosinophilic masses with fragments of dense chromatin are also present. The “stars” in the starry-sky pattern are formed by large cells with pale cytoplasm, the tingible body macrophages. Diagnosis: Follicular hyperplasia in respo...") Tag: Visual edit
08:28, 9 May 2022 Nikolas talk contribs created page File:Tingible body macrophage in lymph node.jpg
08:28, 9 May 2022 Nikolas talk contribs uploaded File:Tingible body macrophage in lymph node.jpg
08:27, 9 May 2022 Nikolas talk contribs created page File:Starry-sky pattern in germinal centre of lymph node.jpg
08:27, 9 May 2022 Nikolas talk contribs uploaded File:Starry-sky pattern in germinal centre of lymph node.jpg
08:27, 9 May 2022 Nikolas talk contribs created page File:Apoptosis in a reactive lymph node (follicular hyperplasia) overview.jpg
08:27, 9 May 2022 Nikolas talk contribs uploaded File:Apoptosis in a reactive lymph node (follicular hyperplasia) overview.jpg
21:40, 7 May 2022 Nikolas talk contribs created page 1. Normal and postmortal pancreas (Created page with "The staining of this slide is HE . This slide shows the pancreas. A part of it is normal, while a part of it is pathological. The part shown on the picture is pathological. A part of it is very pale and eosinophilic compared to the rest of the slide. Upon closer inspection you can see that the cells in this part also lack nuclei. The normal structure and arrangement of the cells is mostly lost, and the remaining cells are less organized. All these characteristics can a...") Tag: Visual edit
21:39, 7 May 2022 Nikolas talk contribs created page File:Postmortem pancreas.jpg
21:39, 7 May 2022 Nikolas talk contribs uploaded File:Postmortem pancreas.jpg
21:39, 7 May 2022 Nikolas talk contribs created page File:Normal pancreas.jpg
21:39, 7 May 2022 Nikolas talk contribs uploaded File:Normal pancreas.jpg
21:38, 7 May 2022 Nikolas talk contribs created page File:Postmortem pancreas overview.jpg
21:38, 7 May 2022 Nikolas talk contribs uploaded File:Postmortem pancreas overview.jpg
21:32, 7 May 2022 Nikolas talk contribs created page Category:Pathology 1 - Histopathology slides (Created page with "Category:Pathology 1") Tag: Visual edit
21:31, 7 May 2022 Nikolas talk contribs created page 50. Grading and staging. Laboratory diagnosis of cancer (Created page with "== Grading and staging == It’s important for physicians to be able to communicate information about tumors in a standard, unambiguous way. By creating criteria, we can more easily determine the clinical behaviour of the tumor. To do this, we created two description protocols for cancers: ''grading'' and ''staging.'' Grading of a cancer describes its ''degree of differentiation'', i.e. how similar the cancer cells are to the corresponding healthy types of cell. A cance...") Tag: Visual edit
21:31, 7 May 2022 Nikolas talk contribs created page File:T stages of CRC.png
21:31, 7 May 2022 Nikolas talk contribs uploaded File:T stages of CRC.png
21:29, 7 May 2022 Nikolas talk contribs created page 49. Clinical aspects of neoplasm. Paraneoplastic syndromes, tumour markers (Created page with "== Clinical aspects of neoplasia == Neoplasms, even benign ones, have clinical consequences, like: * Compression of surrounding tissues * Produce hormones * Erosion, ulceration * Rupture or necrosis of tumour * Cachexia ** <abbr>TNF</abbr>-α * Paraneoplastic syndromes Compression of surrounding tissues is a common problem for neoplasms. Neoplasms in endocrine organs can disrupt the organs ability to produce the hormone. A neoplasm in the pituitary for example could co...") Tag: Visual edit
21:28, 7 May 2022 Nikolas talk contribs created page 48. Microbial carcinogenesis. RNA and DNA viruses. Helicobacter pylori (Created page with "Three types of microbes can be cancerous, RNA viruses, DNA viruses and bacteria. The most important are: * RNA virus ** HTLV-1 (Human T-lymphotropic virus 1) ** HCV (Hepatitis C virus) * DNA virus ** <abbr>EBV</abbr> (Epstein-Barr virus) ** <abbr>HPV</abbr> (Human papillomavirus) ** HBV (Hepatitis B virus) ** HHV8 (Kaposi sarcoma virus) ** Merkel cell polyoma virus * Bacteria ** Helicobacter pylori === RNA viruses === HTLV-1 causes T-cell leukaemias and lymphomas and i...") Tag: Visual edit
21:26, 7 May 2022 Nikolas talk contribs created page 47. Chemical and radiation cancerogenesis. The multistep carcinogenesis of colorectal adenocarcinoma (Created page with "== Chemical carcinogenesis == Cancer isn’t a disease where only one single mutation occurs. Cancer formation has many steps, and doesn’t just require one mutation, but many. This was proven in an animal model for chemical cancerogenesis. Mice were divided into six groups. Most of them were given a carcinogenic compound (polycyclic hydrocarbons, a cancer ''initiator''), and most of them were given a co-carcinogenic compound (croton oil, a cancer ''promoter''). Co-car...") Tag: Visual edit
21:26, 7 May 2022 Nikolas talk contribs created page File:Animal model of chemical carcinogenesis.png
21:26, 7 May 2022 Nikolas talk contribs uploaded File:Animal model of chemical carcinogenesis.png
21:24, 7 May 2022 Nikolas talk contribs created page 46. Tumour suppressor genes II. NF1, NF2, VHL, WT-1 and WT-2. Related syndromes (Created page with "== NF1 == NF1 is a gene that codes for a protein called ''neurofibromin.'' The physiological function of this protein is to stimulate the GTPase activity of Ras, inhibiting it. Mutations in the gene are associated with neurofibromatosis type 1, a disease with many symptoms. The mutation causes tumors to form along the nervous system that can form anywhere in the body. Diagnosis of the disease requires two or more of the following criteria: * Brownish spots on the body,...") Tag: Visual edit
21:23, 7 May 2022 Nikolas talk contribs created page 45. Tumour suppressor genes I. RB and p53. Their role in tumorigenesis. Organ examples (Created page with "Tumour suppressors are the genes that code for the proteins that create the checkpoints in the cell cycle, and their protein products. They work as brakes in the cell proliferation. The G1-S checkpoint checks the DNA for damage while the G2-M checkpoint quality checks the DNA after replication and determines whether it’s safe for the cell to divide. When cells sense DNA damage will the cell cycle stop at the checkpoint until the DNA is repaired, or the cell decides tha...") Tag: Visual edit
21:23, 7 May 2022 Nikolas talk contribs created page File:Pathogenesis of retinoblastoma.png
21:23, 7 May 2022 Nikolas talk contribs uploaded File:Pathogenesis of retinoblastoma.png
21:21, 7 May 2022 Nikolas talk contribs created page 44. The myc oncogene. Types and their changes and role in tumours (c-myc, n-myc). Cell cycle regulators: p16 gene (Created page with "== MYC == Myc is a family of proto-oncogenes that code for transcription factors. The exact physiological function of Myc isn’t entirely understood, however it is rapidly induced when resting cells receive a signal to proliferate, making it an ''immediate early gene'' (IEG)''.'' IEGs are the first genes that are activated in response to a stimulus, such as a proliferation signal. IEGs will then activate other ''late response genes''. We know many functions of the Myc...") Tag: Visual edit
21:21, 7 May 2022 Nikolas talk contribs created page File:Regulators of the cell cycle.png
21:21, 7 May 2022 Nikolas talk contribs uploaded File:Regulators of the cell cycle.png
21:20, 7 May 2022 Nikolas talk contribs created page File:Cell cycle.png
21:20, 7 May 2022 Nikolas talk contribs uploaded File:Cell cycle.png
21:19, 7 May 2022 Nikolas talk contribs created page File:Philadelphia chromosome.png
21:19, 7 May 2022 Nikolas talk contribs uploaded File:Philadelphia chromosome.png
21:18, 7 May 2022 Nikolas talk contribs created page File:Function and signalling cascade of Ras.png
21:18, 7 May 2022 Nikolas talk contribs uploaded File:Function and signalling cascade of Ras.png
21:18, 7 May 2022 Nikolas talk contribs created page 43. Oncogenes and oncoproteins in signal transduction: RAS and RAS-signal proteins. Examples for oncogene with non-receptor tyrosine kinase function. (Created page with "== RAS == The proto-oncogene Ras is a family of a type of signal transduction proteins called ''small GTPases''. They’re associated with G-protein coupled receptors, another receptor type other than ''tyrosine kinase receptor''. The order of signal transduction for Ras proteins go like this: # G-protein coupled receptor binds its ligand, which activates the receptor # The activated receptor causes the Ras protein to bind a GTP, which activates Ras # Ras then activates...") Tag: Visual edit
21:16, 7 May 2022 Nikolas talk contribs created page File:Model of transition from normal epithelium to colorectal carcinoma.png
21:16, 7 May 2022 Nikolas talk contribs uploaded File:Model of transition from normal epithelium to colorectal carcinoma.png
21:15, 7 May 2022 Nikolas talk contribs created page 42. Oncogenes, protooncogenes, oncoproteins. Growth factor and growth factor receptor oncogenes (RET, KIT, PDGFR). Overexpression of normal growth factor receptors (ERBB1, ERBB2). Organ examples. (Created page with "''I recommend starting with the relevant medical biochemistry topic (27 - 28) before getting into this''. All cancers start with some genetic damage. This genetic damage is always ''nonlethal'', meaning that the damage isn’t big enough to actually kill the cell, however it is definitely big enough to cause some serious damage. The process where cancer develops is called ''carcinogenesis''. Nonlethal genetic damage causes mutations and can be due to many factors. Comm...") Tag: Visual edit