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- 20:36, 6 November 2022 Nikolas talk contribs created page 24. Prion disease, spongioform encephalopathy (Created page with "'''Staining''': HE '''Organ''': Brain '''Description''': There is a small region of the grey matter where there are “holes” between neurons. Some vessels resemble these holes. '''Diagnosis''': Prion disease '''Causes''': * Infection by prions '''Theory''': As prions accumulate inside the neurons will the neurons commit apoptosis, which leaves behind small holes between the healthy cells. center|thumb|Overview File:Prion...") Tag: Visual edit
- 20:36, 6 November 2022 Nikolas talk contribs created page File:Prion disease - high magnification.png
- 20:36, 6 November 2022 Nikolas talk contribs uploaded File:Prion disease - high magnification.png
- 20:33, 6 November 2022 Nikolas talk contribs created page File:Prion disease - overview.png
- 20:33, 6 November 2022 Nikolas talk contribs uploaded File:Prion disease - overview.png
- 21:42, 3 November 2022 Nikolas talk contribs created page 23. Senile plaques and neurofibrillar degeneration (Created page with "'''Staining''': Silver stain (Bielschowsky) '''Organ''': Brain, hippocampus '''Description''': The hippocampus is visible and that’s where the characteristic findings are visible on this slide. ''Senile plaques'' are extracellular deposits of β-amyloid that are surrounded by silver-positive proteins. The amyloids themselves aren’t stained by silver and are therefore pale. These plaques are therefore visible as large black foci with a pale core. ''Neurofibrillar...") Tag: Visual edit
- 21:42, 3 November 2022 Nikolas talk contribs created page File:Alzheimer - NFTs.png
- 21:42, 3 November 2022 Nikolas talk contribs uploaded File:Alzheimer - NFTs.png
- 21:42, 3 November 2022 Nikolas talk contribs created page File:Alzheimer - senile plaques.png
- 21:42, 3 November 2022 Nikolas talk contribs uploaded File:Alzheimer - senile plaques.png
- 21:41, 3 November 2022 Nikolas talk contribs created page File:Alzheimer - overview.png
- 21:41, 3 November 2022 Nikolas talk contribs uploaded File:Alzheimer - overview.png
- 21:40, 3 November 2022 Nikolas talk contribs created page 22. Glioblastoma (Created page with "'''Staining''': HE '''Organ''': Brain '''Description''': There are four important characteristics in glioblastomas: * Severe atypia * Many mitotic figures * Pseudopalisading necrosis * Microvascular proliferation Microvascular proliferation is a phenomenon where the tumor contains small capillaries who are irregular and are comprised of atypical endothelial cells. Pseudopalisading necrosis is a phenomenon where the tumor contains areas of necrosis, and this necrosi...") Tag: Visual edit
- 21:40, 3 November 2022 Nikolas talk contribs created page File:Glioblastoma - microvascular proliferation.png
- 21:40, 3 November 2022 Nikolas talk contribs uploaded File:Glioblastoma - microvascular proliferation.png
- 21:39, 3 November 2022 Nikolas talk contribs created page File:Glioblastoma - atypia.png
- 21:39, 3 November 2022 Nikolas talk contribs uploaded File:Glioblastoma - atypia.png
- 21:39, 3 November 2022 Nikolas talk contribs created page File:Glioblastoma - pseudopalisading necrosis.png
- 21:39, 3 November 2022 Nikolas talk contribs uploaded File:Glioblastoma - pseudopalisading necrosis.png
- 21:39, 3 November 2022 Nikolas talk contribs created page File:Glioblastoma - Overview.png
- 21:39, 3 November 2022 Nikolas talk contribs uploaded File:Glioblastoma - Overview.png
- 21:37, 3 November 2022 Nikolas talk contribs created page 21. Oligodendroglioma (Created page with "'''Staining''': HE '''Organ''': Brain '''Description''': Both grey and white matter is visible, although the white matter isn’t very white anymore as it has been invaded by the tumor. The tumor also invades the grey matter, so tumor cells are visible everywhere on the slide. There is cystic degeneration in the upper left corner. Small cells with dark nuclei and a pale “halo” around them are characteristic for oligodendroglioma. This is called “fried egg” m...") Tag: Visual edit
- 21:37, 3 November 2022 Nikolas talk contribs created page File:Oligodendroglioma - chicken wire.png
- 21:37, 3 November 2022 Nikolas talk contribs uploaded File:Oligodendroglioma - chicken wire.png
- 21:36, 3 November 2022 Nikolas talk contribs created page File:Oligodendroglioma - capillaries.png
- 21:36, 3 November 2022 Nikolas talk contribs uploaded File:Oligodendroglioma - capillaries.png
- 21:36, 3 November 2022 Nikolas talk contribs created page File:Oligodendroglioma - fried egg cells.png
- 21:36, 3 November 2022 Nikolas talk contribs uploaded File:Oligodendroglioma - fried egg cells.png
- 21:35, 3 November 2022 Nikolas talk contribs created page File:Oligodendroglioma - nerve cells.png
- 21:35, 3 November 2022 Nikolas talk contribs uploaded File:Oligodendroglioma - nerve cells.png
- 21:35, 3 November 2022 Nikolas talk contribs created page File:Oligodendroglioma - Overview.png
- 21:35, 3 November 2022 Nikolas talk contribs uploaded File:Oligodendroglioma - Overview.png
- 21:33, 3 November 2022 Nikolas talk contribs created page 20. CML-CP smear (Created page with "'''Staining''': May Grunwald-Giemsa '''Organ''': Blood smear '''Description''': There is a marked increase in the number of WBCs compared to normal. Not only mature cells are visible (neutrophils, basophils, eosinophils), but also immature cells. '''Diagnosis''': Chronic phase of chronic myeloid leukaemia '''Causes''': * Philadelphia chromosome (t(9;22)) '''Theory''': ''The CML slide I have is different than the one in class, so there’s no point in an overview...") Tag: Visual edit
- 21:33, 3 November 2022 Nikolas talk contribs created page File:CML - mature and immature cells.png
- 21:33, 3 November 2022 Nikolas talk contribs uploaded File:CML - mature and immature cells.png
- 21:33, 3 November 2022 Nikolas talk contribs created page File:CML - overview.png
- 21:33, 3 November 2022 Nikolas talk contribs uploaded File:CML - overview.png
- 21:31, 3 November 2022 Nikolas talk contribs created page 19. Hodgkin lymphoma (Created page with " '''Staining''': HE '''Organ''': Lymph node '''Description''': The basic structure of the lymph node is lost. Darker, basophilic regions are separated by brighter zones made up of fibrosis. Compared to the slides of most other lymphoid neoplasms are very few of the cells in these basophilic regions tumor cells. The tumor cells are surrounded by a background of reactive inflammatory cells –healthy cells that react to the tumor cells. The characteristic cell type f...") Tag: Visual edit
- 21:31, 3 November 2022 Nikolas talk contribs created page File:Hodgkin lymphoma - high magnification.jpg
- 21:31, 3 November 2022 Nikolas talk contribs uploaded File:Hodgkin lymphoma - high magnification.jpg
- 21:30, 3 November 2022 Nikolas talk contribs created page File:Hodgkin lymphoma - RS cell.jpg
- 21:30, 3 November 2022 Nikolas talk contribs uploaded File:Hodgkin lymphoma - RS cell.jpg
- 21:29, 3 November 2022 Nikolas talk contribs created page File:Hodgkin lymphoma - overview.jpg
- 21:29, 3 November 2022 Nikolas talk contribs uploaded File:Hodgkin lymphoma - overview.jpg
- 21:25, 3 November 2022 Nikolas talk contribs created page 18. Diffuse large B-cell lymphoma (DLBCL) (Created page with "'''Staining''': HE and PAS '''Organ''': Lymph node (not recognizable) '''Description''': No healthy lymph node tissue is visible. The tumor cells form no structures (like glands or nests). The cells are large and show severe atypia/pleiomorphism, almost anaplastic. The cells resemble centroblasts and are therefore said to be centroblastic in appearance or ''centroblastoid.'' There is high mitotic activity (many mitotic figures). On PAS staining are PAS-positive inclu...") Tag: Visual edit
- 21:25, 3 November 2022 Nikolas talk contribs created page File:DLBCL - high magnification.png
- 21:25, 3 November 2022 Nikolas talk contribs uploaded File:DLBCL - high magnification.png
- 21:25, 3 November 2022 Nikolas talk contribs created page File:DLBCL - middle magnification.png
- 21:25, 3 November 2022 Nikolas talk contribs uploaded File:DLBCL - middle magnification.png
- 21:24, 3 November 2022 Nikolas talk contribs created page File:DLBCL - overview.jpg
