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  • 11:00, 20 October 2023 Nikolas talk contribs created page Essential thrombocythaemia (Created page with "'''Essential thrombocythaemia''' (ET) is a myeloproliferative neoplasm characterised by proliferation of the megakaryocyte lineage only. 50% of ET cases are associated with JAK2 mutation. The remaining cases are caused by CALR or MPL mutations. == Clinical features == Most are asymptomatic. Symptoms are related to thrombotic or haemorrhagic episodes. == Diagnosis and evaluation == Labs show: * Normal Hct * Normal RBC * Normal WBC * Elevated thrombocytes Blood sm...") Tag: Visual edit