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- 17:38, 17 February 2023 Nikolas talk contribs created page 43. The work of breathing. Abnormalities of elastic resistance, restrictive disorders (Created page with "== Mechanics of breathing == The pressure in the pleural space, the space between the visceral and parietal layers of the pleura is -4 cmH2O in rest. The intrapleural pressure is -10 cmH2O in the apex of the lung and -2.5 cmH2O in the base of the lung. In other words, the intrapleural pressure is higher at the level of the base than at the level of the apex. This is due to gravity pulling the air down to the base from the apex. To breathe in the thoracic cavity must exp...") Tag: Visual edit