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- 12:53, 26 January 2023 Nikolas talk contribs created page 10. Genetic disorders of hemoglobin (Created page with "== Summary == * Hemoglobin is comprised of four chains, 2 alpha and 2 beta chains, and four heme units * Sickle cell disease occurs after a mutation in the gene for the beta chain * Problems with the gene for the α-chain causes α-thalassemia, while too little β chain cause β-thalassemia * HbA1c is hemoglobin glycated with glucose on the β-globin chain and its level shows the long term average blood glucose level * Every person has 4 genes coding for the alpha chain...") Tag: Visual edit