15. Nodular calcified aortic stenosis

Organ: Aortic valve

Description:

The superior aspect of the preparation is the aortic surface of the valve. The inferior aspect is the ventricular surface.

On the inferior surface the valve has an abnormally small diameter, and small, nodular calcified foci can be seen.

Diagnosis: Nodular calcified aortic stenosis

Causes:

Not significant

Theory:

Aortic stenosis is a type of dystrophic calcification. The aortic valve is normally tricuspid, however a condition called congenital bicuspid aortic valve exists. This bicuspid aortic valve is very predisposed to calcification early in life. The calcification can cause stenosis, which can lead to left ventricular failure. The only treatment is replacement of the valve.