24. Prion disease, spongioform encephalopathy: Difference between revisions

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As prions accumulate inside the neurons will the neurons commit apoptosis, which leaves behind small holes between the healthy cells.
As prions accumulate inside the neurons will the neurons commit apoptosis, which leaves behind small holes between the healthy cells.
[[File:Prion disease - overview.png|thumb|Overview|352x352px]]
[[File:Prion disease - overview.png|thumb|Overview|324x324px]]
[[File:Prion disease - high magnification.png|thumb|Beautiful holes|left|356x356px]]
[[File:Prion disease - high magnification.png|thumb|Beautiful holes|left|320x320px]]
[[Category:Pathology 2 - Histopathology slides]]
[[Category:Pathology 2 - Histopathology slides]]

Latest revision as of 14:09, 7 July 2024

Staining: HE

Organ: Brain

Description:

There is a small region of the grey matter where there are “holes” between neurons. Some vessels resemble these holes.

Diagnosis: Prion disease

Causes:

  • Infection by prions

Theory:

As prions accumulate inside the neurons will the neurons commit apoptosis, which leaves behind small holes between the healthy cells.

Overview
Beautiful holes