11. Hyalinised glomeruli: Difference between revisions
(Created page with "'''Staining''': HE '''Organ''': Kidney '''Description''': Four typical signs can be seen: # Most glomeruli contain globular eosinophilic structures. Some glomeruli are unaffected. # The tubulointerstitium is infiltrated by RBCs, lymphocytes and plasma cells # The tubules contain eosinophilic substance, making they look like the thyroid histologically. This process is called thyroidisation. # Arteriolosclerosis of the vessels in the renal sinus '''Diagnosis''': End-s...") |
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'''Staining''': HE | [[File:Hyalinised glomeruli - overview.png|thumb|Overview]]'''Staining''': HE | ||
'''Organ''': Kidney | '''Organ''': Kidney | ||
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# Arteriolosclerosis of the vessels in the renal sinus | # Arteriolosclerosis of the vessels in the renal sinus | ||
'''Diagnosis''': End-stage chronic kidney disease | '''Diagnosis''': End-stage chronic kidney disease[[File:Hyalinised glomeruli - hyalinised glomeruli vs normal.png|thumb|Hyalinised glomeruli versus healthy ones]]'''Causes''': | ||
'''Causes''': | |||
* Diabetic nephropathy | * Diabetic nephropathy | ||
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Despite the loss of many glomeruli some are still normal and functioning, so the kidney still produces some urine. | Despite the loss of many glomeruli some are still normal and functioning, so the kidney still produces some urine. | ||
[[File:Hyalinised glomeruli - wbcs.png|thumb|The WBCs here are lymphocytes and plasma cells.|left]] | |||
[[File:Hyalinised glomeruli - thyroidisation.png|thumb|Thyroidisation. From the medulla.]] | |||
[[File:Hyalinised glomeruli - wbcs.png | [[File:Hyalinised glomeruli - arteriolosclerosis.png|thumb|From the sinus. Arteriolosclerosis. The affected vessel has a narrowed lumen and the vessel wall is thickened.|left]] | ||
[[File:Hyalinised glomeruli - thyroidisation.png | |||
[[File:Hyalinised glomeruli - arteriolosclerosis.png | |||
[[Category:Pathology 2 - Histopathology slides]] | [[Category:Pathology 2 - Histopathology slides]] |
Revision as of 13:35, 7 July 2024
Staining: HE
Organ: Kidney
Description:
Four typical signs can be seen:
- Most glomeruli contain globular eosinophilic structures. Some glomeruli are unaffected.
- The tubulointerstitium is infiltrated by RBCs, lymphocytes and plasma cells
- The tubules contain eosinophilic substance, making they look like the thyroid histologically. This process is called thyroidisation.
- Arteriolosclerosis of the vessels in the renal sinus
Diagnosis: End-stage chronic kidney disease
Causes:
- Diabetic nephropathy
- Chronic pyelonephritis
- Rapidly progressing glomerulonephritis
- Glomerulonephritis
Theory:
Hyalinisation of the glomeruli is the morphology of the end-stage kidney disease (chronic renal failure), which is often the end-result of the conditions mentioned above.
Despite the loss of many glomeruli some are still normal and functioning, so the kidney still produces some urine.