25. Epidemiology and prevention of ulcer disease: Difference between revisions
(Created page with "* Epidemiology ** Men > women ** 25 – 60 years ** Duodenal ulcers 4x more common than gastric, more common in younger ** Incidence dropping globally * Aggressive factors ** HCl ** Pepsin ** Decreased motility ** H. pylori *** 6 – 10x increased risk in H. pylori *** 50% of the world is infected *** Lifetime risk 10% in H. P negatives and 20% in positives * Protective factors ** Thanks to prostaglandins ** Mucosal blood flow ** Mucin ** Bicarbonate secretion ** Restitu...") |
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*** Elimination of aggressive factors | *** Elimination of aggressive factors | ||
*** Increased fibre | *** Increased fibre | ||
*** Decrease caffeine | *** Decrease caffeine | ||
*** Decrease alcohol | *** Decrease alcohol | ||
Latest revision as of 13:08, 16 January 2024
- Epidemiology
- Men > women
- 25 – 60 years
- Duodenal ulcers 4x more common than gastric, more common in younger
- Incidence dropping globally
- Aggressive factors
- HCl
- Pepsin
- Decreased motility
- H. pylori
- 6 – 10x increased risk in H. pylori
- 50% of the world is infected
- Lifetime risk 10% in H. P negatives and 20% in positives
- Protective factors
- Thanks to prostaglandins
- Mucosal blood flow
- Mucin
- Bicarbonate secretion
- Restitution
- Regeneration
- Etiology
- Old age
- Long-term NSAID
- Long-term steroid
- Smoking
- Alcohol
- H. pylori infection
- Stress
- Prevention
- Primary
- Enhancement of protective factors
- Elimination of aggressive factors
- Increased fibre
- Decrease caffeine
- Decrease alcohol
- Prevent smoking
- Secondary – screening
- Urea breath test
- Blood antibody test
- Gastroscopy
- Tertiary – treatment
- PPIs, H2 blockers
- Eradicate H. pylori
- Stop NSAIDs, steroids
- Improve diet
- Stop smoking
- Primary