26B. Subacute combined degeneration of the spinal cord: Difference between revisions
(Created page with "Subacute combined degeneration of the spinal cord, also called funicular myelosis, is a degeneration of the dorsal and lateral white matter of the spinal cord which occurs due to chronic B12 deficiency. The spinocerebellar, lateral corticospinal, and dorsal columns are affected. == Clinical features == The patient has loss of deep sensation, vibration, and position sense. Sensory ataxia is also present. == Diagnosis and evaluation == Megaloblastic anaemia may be prese...") |
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Subacute combined degeneration of the spinal cord, also called funicular myelosis, is a degeneration of the dorsal and lateral white matter of the spinal cord which occurs due to chronic B12 deficiency. | Subacute combined degeneration of the spinal cord, also called funicular myelosis, is a degeneration of the dorsal and lateral white matter of the spinal cord which occurs due to chronic B12 deficiency. Some conditions, like chronic nitrous oxide abuse, can cause a functional B12 deficiency. | ||
The spinocerebellar, lateral corticospinal, and dorsal columns are affected. | The spinocerebellar, lateral corticospinal, and dorsal columns are affected. | ||
Latest revision as of 20:34, 7 August 2023
Subacute combined degeneration of the spinal cord, also called funicular myelosis, is a degeneration of the dorsal and lateral white matter of the spinal cord which occurs due to chronic B12 deficiency. Some conditions, like chronic nitrous oxide abuse, can cause a functional B12 deficiency.
The spinocerebellar, lateral corticospinal, and dorsal columns are affected.
Clinical features
The patient has loss of deep sensation, vibration, and position sense. Sensory ataxia is also present.
Diagnosis and evaluation
Megaloblastic anaemia may be present, as well as low serum B12 and high MMA and homocysteine.
Treatment
Treatment is B12 supplementation. It may take a long time for the symptoms to improve, and they may not completely resolve.