17. CLL or SLL infiltration in lymph node: Difference between revisions
(Created page with "'''Staining''': HE '''Organ''': Lymph node '''Description''': It’s obvious that this is a lymph node, however the normal architecture is absent. The lymph node is filled by the tumor cells, which have destroyed the normal structure of the lymph node. The tumor cells themselves show only mild atypia/pleiomorphism. They resemble centrocytes and are therefore ''centrocytic'' or ''centrocytoid.'' '''Diagnosis''': Chronic lymphocytic leukaemia '''Causes''': * Not well...") |
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It’s obvious that this is a lymph node, however the normal architecture is absent. The lymph node is filled by the tumor cells, which have destroyed the normal structure of the lymph node. The tumor cells themselves show only mild atypia/pleiomorphism. They resemble centrocytes and are therefore ''centrocytic'' or ''centrocytoid.'' | It’s obvious that this is a lymph node, however the normal architecture is absent. The lymph node is filled by the tumor cells, which have destroyed the normal structure of the lymph node. The tumor cells themselves show only mild atypia/pleiomorphism. They resemble centrocytes and are therefore ''centrocytic'' or ''centrocytoid.'' | ||
'''Diagnosis''' | '''Diagnosis:''' Small lymphocytic lymphoma (or chronic lymphocytic leukaemia) | ||
'''Causes''' | '''Causes:''' | ||
* Not well known | * Not well known | ||
'''Theory''' | '''Theory:''' | ||
CLL/SLL is the most frequent adult leukaemia. Because this slide shows affection of a lymph node, this is most likely SLL (although it could be CLL with lymph node affection as well).[[File:CLL - overview.png|center|thumb|Overview. No follicles, no cortex, no medulla, no sinuses.]] | |||
[[File:CLL - overview.png|center|thumb|Overview. No follicles, no cortex, no medulla, no sinuses.]] | |||
[[File:CLL - high magnification.png|center|thumb|Nice-looking cells.]] | [[File:CLL - high magnification.png|center|thumb|Nice-looking cells.]] | ||
[[Category:Pathology 2 - Histopathology slides]] | [[Category:Pathology 2 - Histopathology slides]] | ||
Revision as of 17:24, 15 April 2023
Staining: HE
Organ: Lymph node
Description:
It’s obvious that this is a lymph node, however the normal architecture is absent. The lymph node is filled by the tumor cells, which have destroyed the normal structure of the lymph node. The tumor cells themselves show only mild atypia/pleiomorphism. They resemble centrocytes and are therefore centrocytic or centrocytoid.
Diagnosis: Small lymphocytic lymphoma (or chronic lymphocytic leukaemia)
Causes:
- Not well known
Theory:
CLL/SLL is the most frequent adult leukaemia. Because this slide shows affection of a lymph node, this is most likely SLL (although it could be CLL with lymph node affection as well).
