40. Paget disease of the breast: Difference between revisions

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[[File:Paget disease of the breast - overview.png|thumb|Overview|415x415px]]'''Staining''': HE
[[File:Paget disease of the breast - overview.png|thumb|Overview|382x382px]]'''Staining''': HE


'''Organ''': Nipple
'''Organ''': Nipple

Revision as of 14:40, 7 July 2024

Overview

Staining: HE

Organ: Nipple

Description:

The squamous cells of the epidermis are replaced by tumor cells showing significant atypia.

The actual tumor or DCIS is not visible on this slide.

Diagnosis: Paget disease of the breast

Causes:

  • Cancer cells invading the epidermis of the nipple

Theory:

Paget disease of the breast can occur both in DCIS and in invasive carcinoma. It can look like eczema.

Left: Area of Paget disease. Right: Area unaffected by tumor cells. Both pictures are taken from the same slide but from different areas.