20. DIC (fibrinthrombi in kidney) (fibrin stain): Difference between revisions
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Many parts of the slide are darker, but especially the glomeruli are very dark blue, sometimes black. Some tubules are also dark. | Many parts of the slide are darker, but especially the glomeruli are very dark blue, sometimes black. Some tubules are also dark. | ||
'''Diagnosis''': | '''Diagnosis''': DIC – phase 1 | ||
'''Theory''': | '''Theory''': | ||
In phase I | In phase I of disseminated intravascular coagulopathy (DIC), the thrombotic phase, will there be microthrombus and microembolism formation in every organ. In the kidney are the glomerular capillaries especially affected by this. | ||
Some tubules also appear to be fibrin-positive, however this is a ''false positive'' result. There is no fibrin inside the tubule cells. | Some tubules also appear to be fibrin-positive, however this is a ''false positive'' result. There is no fibrin inside the tubule cells. | ||
Revision as of 12:41, 5 July 2024
Staining: Weigert (fibrin) stain
Organ: Kidney
Description:
Many parts of the slide are darker, but especially the glomeruli are very dark blue, sometimes black. Some tubules are also dark.
Diagnosis: DIC – phase 1
Theory:
In phase I of disseminated intravascular coagulopathy (DIC), the thrombotic phase, will there be microthrombus and microembolism formation in every organ. In the kidney are the glomerular capillaries especially affected by this.
Some tubules also appear to be fibrin-positive, however this is a false positive result. There is no fibrin inside the tubule cells.
