2. Esophageal carcinoma: Difference between revisions
(Created page with "'''Organ''': Oesophagus '''Description''': We can see that the mucosa of the oesophagus is normal, except on the lower part. On that part is the mucosa ulcerated. '''Diagnosis''': Probably oesophageal adenocarcinoma, unlikely oesophageal squamous cell carcinoma '''Risk factors:''' * Oesophageal adenocarcinoma ** Barret’s metaplasia (gastro-oesophageal reflux disease) * Oesophageal squamous cell carcinoma ** Smoking ** Alcohol ** Poor hygiene '''Theory''': Two ma...") |
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'''Organ''': Oesophagus | [[File:Oesophageal carcinoma prep.jpg|thumb|Not the best picture and not the best preparation. You can vaguely see where the normal mucosa stops and the abnormal mucosa starts.|577x577px]]'''Organ''': Oesophagus | ||
'''Description''': | '''Description''': | ||
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Ulcerating tumors don’t protrude into the lumen but ulcerates the mucosal surface. This may cause melena. This preparation is of this type. | Ulcerating tumors don’t protrude into the lumen but ulcerates the mucosal surface. This may cause melena. This preparation is of this type. | ||
[[Category:Pathology 2 - Macropreparations]] | [[Category:Pathology 2 - Macropreparations]] | ||
Latest revision as of 13:40, 7 July 2024
Organ: Oesophagus
Description:
We can see that the mucosa of the oesophagus is normal, except on the lower part. On that part is the mucosa ulcerated.
Diagnosis: Probably oesophageal adenocarcinoma, unlikely oesophageal squamous cell carcinoma
Risk factors:
- Oesophageal adenocarcinoma
- Barret’s metaplasia (gastro-oesophageal reflux disease)
- Oesophageal squamous cell carcinoma
- Smoking
- Alcohol
- Poor hygiene
Theory:
Two major types of oesophageal cancer exist according to microscopy: squamous cell carcinoma and adenocarcinoma.
Oesophageal adenocarcinoma mostly affects the lower parts, which is why this preparation is most likely an adenocarcinoma. The major risk factor is gastro-oesophageal reflux disease, which again is associated with obesity, which has become more common the last decades.
Oesophageal cancer is also classified according to the macroscopy; we can have polypoid types or ulcerating types.
Polypoid tumors produce “polyps” that protrude into the lumen and obstruct it. It is the most common type.
Ulcerating tumors don’t protrude into the lumen but ulcerates the mucosal surface. This may cause melena. This preparation is of this type.