45. Nodular melanoma: Difference between revisions

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(Created page with "'''Staining''': HE '''Organ''': Skin '''Description''': Like the name implies the tumor forms a nodule. The tumor cells are highly atypical, bordering on anaplastic. Some of the tumor cells contain melanin. Tumor cells are present in the epidermis as well. '''Diagnosis''': Nodular melanoma '''Causes''': * Sun exposure '''Theory''': The presence of tumor cells in the epidermis is essential to establish the diagnosis of ''primary'' melanoma. If there were no tumor...")
 
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'''Staining''': HE
[[File:Nodular melanoma - overview.png|thumb|Overview|376x376px]]'''Staining''': HE


'''Organ''': Skin
'''Organ''': Skin
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* Sun exposure
* Sun exposure
 
[[File:Nodular melanoma - melanin.png|thumb|Tumour cells containing melanin|274x274px]]'''Theory''':
'''Theory''':


The presence of tumor cells in the epidermis is essential to establish the diagnosis of ''primary'' melanoma. If there were no tumor cells there the lesion could have been a melanoma metastasis rather than the primary tumor.
The presence of tumor cells in the epidermis is essential to establish the diagnosis of ''primary'' melanoma. If there were no tumor cells there the lesion could have been a melanoma metastasis rather than the primary tumor.
[[File:Nodular melanoma - overview.png|center|thumb|Overview]]
[[File:Nodular melanoma - atypia.png|thumb|Severe atypia, or even anaplasia|left]]
[[File:Nodular melanoma - melanin.png|center|thumb|Tumour cells containing melanin]]
[[File:Nodular melanoma - epidermis.png|thumb|Tumour cells in the epidermis|273x273px]]
[[File:Nodular melanoma - atypia.png|center|thumb|Severe atypia, or even anaplasia]]
[[File:Nodular melanoma - epidermis.png|center|thumb|Tumour cells in the epidermis]]
[[Category:Pathology 2 - Histopathology slides]]
[[Category:Pathology 2 - Histopathology slides]]

Latest revision as of 14:51, 7 July 2024

Overview

Staining: HE

Organ: Skin

Description:

Like the name implies the tumor forms a nodule. The tumor cells are highly atypical, bordering on anaplastic. Some of the tumor cells contain melanin.

Tumor cells are present in the epidermis as well.

Diagnosis: Nodular melanoma

Causes:

  • Sun exposure
Tumour cells containing melanin

Theory:

The presence of tumor cells in the epidermis is essential to establish the diagnosis of primary melanoma. If there were no tumor cells there the lesion could have been a melanoma metastasis rather than the primary tumor.

Severe atypia, or even anaplasia
Tumour cells in the epidermis