Kaposi sarcoma: Difference between revisions

Latest revision as of 09:15, 14 August 2024

Caused by HHV8, immunosuppression is risk factor
Malignant tumor of endothelial cells
4 types
- Classic – in older males
- Endemic – in Africa
- Immunosuppressive therapy-related
- AIDS-related
Clinical features
- Multiple cutaneous lesions
  - Purplish macules -> patches -> papules -> plaques -> nodules
- Rapidly growing
- Initially seen on face, oral cavity or chest
- Organs can be involved
Treatment
- Classic KS -> surgery or radiotherapy
- HIV-related KS -> treatment of AIDS alone may cause cancer regression
- KS associated with non-HIV immunosuppression -> changing immunosuppressing drug alone may cause regression

@@ Line 1: / Line 1: @@
-<section begin="dermatology" />* Caused by HHV8
+<section begin="oncology" /><section begin="dermatology" />* Caused by HHV8, immunosuppression is risk factor
 * Malignant tumor of endothelial cells
 * 4 types
@@ Line 13: / Line 13: @@
 ** Organs can be involved
 * Treatment
-** Vinblastine
+** Classic KS -> surgery or radiotherapy
-** Radiotherapy
+** HIV-related KS -> treatment of AIDS alone may cause cancer regression
-** Treat underlying HIV<section end="dermatology" />
+** KS associated with non-HIV immunosuppression -> changing immunosuppressing drug alone may cause regression<section end="dermatology" /><section end="oncology" />
 [[Category:Dermatology]]
 [[Category:Oncology]]