49. Giant cell tumor of bone (osteoclastoma): Difference between revisions

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(Created page with "'''Staining''': HE '''Organ''': Bone tumor sampled by curettage '''Description''': The purplish things are pieces of the tumor. The pinkish things are not. The tumor pieces are comprised of two types of cell. There are osteoclast-type giant cells, which have large eosinophilic cytoplasm and many nuclei. These cells are not neoplastic; they are reactive cells. The cells that are between the giant cells are the neoplastic cells. These cells are primitive mesenchymal c...")
 
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'''Staining''': HE
[[File:Giant cell tumour of bone - overview.png|thumb|Overview|454x454px]]'''Staining''': HE


'''Organ''': Bone tumor sampled by curettage
'''Organ''': Bone tumor sampled by curettage
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The old name for this tumor is “osteoclastoma”.
The old name for this tumor is “osteoclastoma”.
[[File:Giant cell tumour of bone - overview.png|center|thumb|Overview]]
[[File:Giant cell tumour of bone - giant cell.png|thumb|Osteoclast-type giant cell|left|303x303px]]
[[File:Giant cell tumour of bone - giant cell.png|center|thumb|Osteoclast-type giant cell]]
[[File:Giant cell tumour of bone - giant cell2.png|thumb|High magnification giant cell|307x307px]]
[[File:Giant cell tumour of bone - giant cell2.png|center|thumb|High magnification giant cell]]
[[Category:Pathology 2 - Histopathology slides]]
[[Category:Pathology 2 - Histopathology slides]]

Latest revision as of 14:56, 7 July 2024

Overview

Staining: HE

Organ: Bone tumor sampled by curettage

Description:

The purplish things are pieces of the tumor. The pinkish things are not.

The tumor pieces are comprised of two types of cell. There are osteoclast-type giant cells, which have large eosinophilic cytoplasm and many nuclei. These cells are not neoplastic; they are reactive cells.

The cells that are between the giant cells are the neoplastic cells. These cells are primitive mesenchymal cells with poorly defined cytoplasm.

Diagnosis: Giant cell tumor of bone

Risk factors:

  • Age 20 – 45

Theory:

The old name for this tumor is “osteoclastoma”.

Osteoclast-type giant cell
High magnification giant cell