45. Nodular melanoma: Difference between revisions
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* Sun exposure | * Sun exposure | ||
[[File:Nodular melanoma - melanin.png|thumb|Tumour cells containing melanin]]'''Theory''': | [[File:Nodular melanoma - melanin.png|thumb|Tumour cells containing melanin|274x274px]]'''Theory''': | ||
The presence of tumor cells in the epidermis is essential to establish the diagnosis of ''primary'' melanoma. If there were no tumor cells there the lesion could have been a melanoma metastasis rather than the primary tumor. | The presence of tumor cells in the epidermis is essential to establish the diagnosis of ''primary'' melanoma. If there were no tumor cells there the lesion could have been a melanoma metastasis rather than the primary tumor. | ||
[[File:Nodular melanoma - atypia.png|thumb|Severe atypia, or even anaplasia|left]] | [[File:Nodular melanoma - atypia.png|thumb|Severe atypia, or even anaplasia|left]] | ||
[[File:Nodular melanoma - epidermis.png|thumb|Tumour cells in the epidermis]] | [[File:Nodular melanoma - epidermis.png|thumb|Tumour cells in the epidermis|273x273px]] | ||
[[Category:Pathology 2 - Histopathology slides]] | [[Category:Pathology 2 - Histopathology slides]] | ||
Latest revision as of 15:51, 7 July 2024
Staining: HE
Organ: Skin
Description:
Like the name implies the tumor forms a nodule. The tumor cells are highly atypical, bordering on anaplastic. Some of the tumor cells contain melanin.
Tumor cells are present in the epidermis as well.
Diagnosis: Nodular melanoma
Causes:
- Sun exposure
Theory:
The presence of tumor cells in the epidermis is essential to establish the diagnosis of primary melanoma. If there were no tumor cells there the lesion could have been a melanoma metastasis rather than the primary tumor.
