17. CLL or SLL infiltration in lymph node: Difference between revisions
(Created page with "'''Staining''': HE '''Organ''': Lymph node '''Description''': It’s obvious that this is a lymph node, however the normal architecture is absent. The lymph node is filled by the tumor cells, which have destroyed the normal structure of the lymph node. The tumor cells themselves show only mild atypia/pleiomorphism. They resemble centrocytes and are therefore ''centrocytic'' or ''centrocytoid.'' '''Diagnosis''': Chronic lymphocytic leukaemia '''Causes''': * Not well...") |
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'''Staining''': HE | [[File:CLL - overview.png|thumb|Overview. No follicles, no cortex, no medulla, no sinuses.|407x407px]]'''Staining''': HE | ||
'''Organ''': Lymph node | '''Organ''': Lymph node | ||
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It’s obvious that this is a lymph node, however the normal architecture is absent. The lymph node is filled by the tumor cells, which have destroyed the normal structure of the lymph node. The tumor cells themselves show only mild atypia/pleiomorphism. They resemble centrocytes and are therefore ''centrocytic'' or ''centrocytoid.'' | It’s obvious that this is a lymph node, however the normal architecture is absent. The lymph node is filled by the tumor cells, which have destroyed the normal structure of the lymph node. The tumor cells themselves show only mild atypia/pleiomorphism. They resemble centrocytes and are therefore ''centrocytic'' or ''centrocytoid.'' | ||
'''Diagnosis''' | '''Diagnosis:''' Small lymphocytic lymphoma (or chronic lymphocytic leukaemia)[[File:CLL - high magnification.png|thumb|Nice-looking cells.|398x398px]]'''Risk factors:''' Not well known | ||
''' | '''Theory:''' | ||
CLL/SLL is the most frequent adult leukaemia. Because this slide shows affection of a lymph node, this is most likely SLL (although it could be CLL with lymph node affection as well). | |||
[[Category:Pathology 2 - Histopathology slides]] | [[Category:Pathology 2 - Histopathology slides]] | ||
Latest revision as of 14:46, 7 July 2024
Staining: HE
Organ: Lymph node
Description:
It’s obvious that this is a lymph node, however the normal architecture is absent. The lymph node is filled by the tumor cells, which have destroyed the normal structure of the lymph node. The tumor cells themselves show only mild atypia/pleiomorphism. They resemble centrocytes and are therefore centrocytic or centrocytoid.
Diagnosis: Small lymphocytic lymphoma (or chronic lymphocytic leukaemia)
Risk factors: Not well known
Theory:
CLL/SLL is the most frequent adult leukaemia. Because this slide shows affection of a lymph node, this is most likely SLL (although it could be CLL with lymph node affection as well).