20. Polycystic kidney (adult type): Difference between revisions
(Created page with "'''Organ''': Liver and kidney '''Description''': The liver contains only small cysts, shown here as holes. The kidney is very large and contains many large cysts to such a degree that very little kidney parenchyme is actually left. Some cysts are even 3-5 cm in diameter. '''Diagnosis''': Autosomal dominant polycystic kidney disease '''Causes''': * Autosomal dominant mutation of the PKD1 gene '''Theory''': In autosomal dominant polycystic kidney disease will the p...") |
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'''Organ''': Liver and kidney | [[File:Polycystic kidney disease (adult type) prep front.jpg|thumb|Polycystic kidney disease (adult type) prep front|352x352px]]'''Organ''': Liver and kidney | ||
'''Description''': | '''Description''': | ||
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* Autosomal dominant mutation of the PKD1 gene | * Autosomal dominant mutation of the PKD1 gene | ||
'''Theory''': | '''Theory''':[[File:Polycystic kidney disease (adult type) prep back.jpg|thumb|Polycystic kidney disease (adult type) prep back|343x343px]]In autosomal dominant polycystic kidney disease will the progressive loss of kidney parenchyme lead to chronic renal failure in the patient’s 40s. This preparation is taken from a patient around this age, as this person’s kidney parenchyme is already largely replaced by cysts. | ||
In autosomal dominant polycystic kidney disease will the progressive loss of kidney parenchyme lead to chronic renal failure in the patient’s 40s. This preparation is taken from a patient around this age, as this person’s kidney parenchyme is already largely replaced by cysts. | |||
This form of polycystic kidney disease causes no functional abnormality of the liver. The small liver cysts are not large enough to cause liver failure. | This form of polycystic kidney disease causes no functional abnormality of the liver. The small liver cysts are not large enough to cause liver failure. | ||
[[Category:Pathology 2 - Macropreparations]] | [[Category:Pathology 2 - Macropreparations]] | ||
Latest revision as of 13:46, 7 July 2024
_prep_front.jpg)
Organ: Liver and kidney
Description:
The liver contains only small cysts, shown here as holes.
The kidney is very large and contains many large cysts to such a degree that very little kidney parenchyme is actually left. Some cysts are even 3-5 cm in diameter.
Diagnosis: Autosomal dominant polycystic kidney disease
Causes:
- Autosomal dominant mutation of the PKD1 gene
Theory:
_prep_back.jpg)
In autosomal dominant polycystic kidney disease will the progressive loss of kidney parenchyme lead to chronic renal failure in the patient’s 40s. This preparation is taken from a patient around this age, as this person’s kidney parenchyme is already largely replaced by cysts.
This form of polycystic kidney disease causes no functional abnormality of the liver. The small liver cysts are not large enough to cause liver failure.