58. Silicosis: Difference between revisions

From greek.doctor
VisualWikitext
No edit summary
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:
'''Organ''': Lung + lymph nodes
[[File:Silicosis prep front.jpg|thumb|Silicosis prep front]]'''Organ''': Lung + lymph nodes


'''Description''':
'''Description''':
Line 9: Line 9:
'''Diagnosis''': Silicosis
'''Diagnosis''': Silicosis


'''Causes''':
'''Causes''': Silica dust inhalation


* Occupational disease, silica dust inhalation
'''Theory''':


'''Theory''':[[File:Silicosis prep front.jpg|thumb|Silicosis prep front]]Several occupations are associated with exposure to silica dust, like miners and stone cutters. When these people inhale the dust, it will be eaten by alveolar macrophages. However, because the silica dust is inorganic can’t the macrophages break it down. The macrophages respond by producing cytokines that recruit fibroblasts. Progressive fibrosis occurs.
Several occupations are associated with exposure to silica dust, like miners and stone cutters. When these people inhale the dust, it will be eaten by alveolar macrophages. However, because the silica dust is inorganic can’t the macrophages break it down. The macrophages respond by producing cytokines that recruit fibroblasts. Progressive fibrosis occurs. In this preparation are silicotic nodules not ''macroscopically'' visible in the lung parenchyme, however histology of the lung would definitely show those nodules. However, we can see silicotic nodules as greyish dots inside the hilar and mediastinal lymph nodes. Anthracosis in this preparation is also severe, because workers that are exposed to silica crystals are also exposed to high amounts of coal and carbon dust.[[File:Silicosis prep side.jpg|center|thumb|Silicosis prep side]]
 
In this preparation are silicotic nodules not ''macroscopically'' visible in the lung parenchyme, however histology of the lung would definitely show those nodules. However, we can see silicotic nodules as greyish dots inside the hilar and mediastinal lymph nodes.
 
Anthracosis in this preparation is also severe, because workers that are exposed to silica crystals are also exposed to high amounts of coal and carbon dust.
[[File:Silicosis prep side.jpg|center|thumb|Silicosis prep side]]
[[Category:Pathology 1 - Macropreparations]]
[[Category:Pathology 1 - Macropreparations]]

Latest revision as of 10:41, 5 July 2024

Silicosis prep front

Organ: Lung + lymph nodes

Description:

The lung parenchyme shows many black foci of anthracosis.

In the hilar and mediastinal lymph nodes we can see anthracosis here too, but small greyish dots as well.

Diagnosis: Silicosis

Causes: Silica dust inhalation

Theory:

Several occupations are associated with exposure to silica dust, like miners and stone cutters. When these people inhale the dust, it will be eaten by alveolar macrophages. However, because the silica dust is inorganic can’t the macrophages break it down. The macrophages respond by producing cytokines that recruit fibroblasts. Progressive fibrosis occurs. In this preparation are silicotic nodules not macroscopically visible in the lung parenchyme, however histology of the lung would definitely show those nodules. However, we can see silicotic nodules as greyish dots inside the hilar and mediastinal lymph nodes. Anthracosis in this preparation is also severe, because workers that are exposed to silica crystals are also exposed to high amounts of coal and carbon dust.

Silicosis prep side