Pancreatic endocrine tumours: Difference between revisions
(Created page with "Pancreatic endocrine tumours are neuroendocrine tumours, which produce hormones. They originate from the Langerhans islets cells. They account for < 5% of pancreatic tumours and are therefore quite rare. These tumours are predominantly benign but may be malignant as well. However, their disruptive potential comes rather from their hormone-producing properties rather than their mass effect or invasion. A few percent of endocrine pancreatic tumours are associated with mu...") |
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Pancreatic endocrine tumours are neuroendocrine tumours, which produce hormones. They originate from the Langerhans islets cells. They account for < 5% of pancreatic tumours and are therefore quite rare. | '''Pancreatic endocrine tumours''' are [[Neuroendocrine tumour|neuroendocrine tumours]], which produce hormones. They originate from the Langerhans islets cells. They account for < 5% of pancreatic tumours and are therefore quite rare. | ||
These tumours are predominantly benign but may be malignant as well. However, their disruptive potential comes rather from their hormone-producing properties rather than their mass effect or invasion. | These tumours are predominantly benign but may be malignant as well. However, their disruptive potential comes rather from their hormone-producing properties rather than their mass effect or invasion. | ||
A few percent of endocrine pancreatic tumours are associated with multiple endocrine neoplasia (MEN) type 1. | A few percent of endocrine pancreatic tumours are associated with [[Multiple endocrine neoplasia type 1|multiple endocrine neoplasia (MEN) type 1]]. | ||
The tumours are named after the hormone they produce: | The tumours are named after the hormone they produce: | ||
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* Somatostatinoma | * Somatostatinoma | ||
Insulinomas cause hypoglycaemia, gastrinomas cause severe peptic ulcer disease, VIPomas cause secretory diarrhoea, and so on. | Insulinomas cause [[hypoglycaemia]], gastrinomas cause severe [[peptic ulcer disease]], VIPomas cause secretory diarrhoea, and so on. | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Gastrointestinal surgery]] | [[Category:Gastrointestinal surgery]] | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
Latest revision as of 11:10, 2 November 2023
Pancreatic endocrine tumours are neuroendocrine tumours, which produce hormones. They originate from the Langerhans islets cells. They account for < 5% of pancreatic tumours and are therefore quite rare.
These tumours are predominantly benign but may be malignant as well. However, their disruptive potential comes rather from their hormone-producing properties rather than their mass effect or invasion.
A few percent of endocrine pancreatic tumours are associated with multiple endocrine neoplasia (MEN) type 1.
The tumours are named after the hormone they produce:
- Insulinoma
- Gastrinoma
- VIPoma
- Glucagonoma
- Somatostatinoma
Insulinomas cause hypoglycaemia, gastrinomas cause severe peptic ulcer disease, VIPomas cause secretory diarrhoea, and so on.