69. Nitroimidazoles. RNA polymerase inhibitors: Revision history

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23 April 2023

  • curprev 17:4517:45, 23 April 2023‎ Nikolas talk contribs‎ 3,080 bytes +3,080‎ Created page with "''RNA polymerase inhibitors include the macrocyclines and rifamycins''. == Nitroimidazoles == === Compounds === * Metronidazole * Tinidazole The most important nitroimidazole is metronidazole, but tinidazole is very similar. === Mechanism of action === Nitroimidazoles are prodrugs which are metabolized into reactive metabolites by enzymes inside the pathogen cell. The reactive metabolites then bind to and damage DNA and proteins. This effect is bactericidal. === Me..." Tag: Visual edit