48. Pathobiochemistry of the late complications of diabetes mellitus: Revision history

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2 March 2023

  • curprev 10:4610:46, 2 March 2023‎ Nikolas talk contribs‎ 2,735 bytes +2,735‎ Created page with "As explained in the previous topic are these four factors important in the development of microvascular disease in diabetes mellitus. == Pseudohypoxia == As already explained will hyperglycaemia increase the activity of the polyol pathway, which depletes NADPH and increases the NADH/NAD+ ratio. The latter causes a metabolic state of cells that is similar to hypoxia, called pseudohypoxia. The affected cells produce less ATP and more free radicals. Also, the amount of gly..." Tag: Visual edit