View source for 49. Giant cell tumor of bone (osteoclastoma)

[[File:Giant cell tumour of bone - overview.png|thumb|Overview|454x454px]]'''Staining''': HE

'''Organ''': Bone tumor sampled by curettage

'''Description''':

The purplish things are pieces of the tumor. The pinkish things are not.

The tumor pieces are comprised of two types of cell. There are osteoclast-type giant cells, which have large eosinophilic cytoplasm and many nuclei. These cells are not neoplastic; they are reactive cells.

The cells that are between the giant cells are the neoplastic cells. These cells are primitive mesenchymal cells with poorly defined cytoplasm.

'''Diagnosis''': Giant cell tumor of bone

'''Risk factors:'''

* Age 20 – 45

'''Theory''':

The old name for this tumor is “osteoclastoma”.
[[File:Giant cell tumour of bone - giant cell.png|thumb|Osteoclast-type giant cell|left|303x303px]]
[[File:Giant cell tumour of bone - giant cell2.png|thumb|High magnification giant cell|307x307px]]
[[Category:Pathology 2 - Histopathology slides]]