47. Bullous pemphigoid: Difference between revisions

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(Created page with "'''Staining''': HE '''Organ''': Skin '''Description''': Bullous pemphigoid is characterized by subepidermal nonancantholytic blisters. The main finding here is that the epidermis has been separated from the basement membrane it is usually attached to. This forms a bulla between the epidermis and the basement membrane. This bulla is filled with low-protein fluid and eosinophils. '''Diagnosis''': Bullous pemphigoid '''Causes''': * Unknown '''Theory''': Blisters in...")
 
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'''Staining''': HE
[[File:Bullous pemphigoid - overview.png|thumb|Overview]]'''Staining''': HE


'''Organ''': Skin
'''Organ''': Skin
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Bullous pemphigoid is characterized by subepidermal nonancantholytic blisters. The main finding here is that the epidermis has been separated from the basement membrane it is usually attached to. This forms a bulla between the epidermis and the basement membrane. This bulla is filled with low-protein fluid and eosinophils.
Bullous pemphigoid is characterized by subepidermal nonancantholytic blisters. The main finding here is that the epidermis has been separated from the basement membrane it is usually attached to. This forms a bulla between the epidermis and the basement membrane. This bulla is filled with low-protein fluid and eosinophils.


'''Diagnosis''': Bullous pemphigoid
'''Diagnosis''': Bullous pemphigoid[[File:Bullous pemphigoid - high magnification.png|thumb|High magnification picture]]'''Causes''':
 
'''Causes''':


* Unknown
* Unknown
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Bullous pemhpigoid and pemphgoid vulgaris share a similar pathogenic mechanism, but differ in clinical representation due to variation in the antigen targeted. Hemidesmosomes in bullous pemphigoid and desmosomes in pemhigus vulgaris.
Bullous pemhpigoid and pemphgoid vulgaris share a similar pathogenic mechanism, but differ in clinical representation due to variation in the antigen targeted. Hemidesmosomes in bullous pemphigoid and desmosomes in pemhigus vulgaris.
[[File:Bullous pemphigoid - overview.png|center|thumb|Overview]]
[[File:Bullous pemphigoid - high magnification.png|center|thumb|High magnification picture]]
[[Category:Pathology 2 - Histopathology slides]]
[[Category:Pathology 2 - Histopathology slides]]