3. Coeliac disease – total villus atrophy (Marsh 3c): Difference between revisions

In addition to this is Marsh 3 divided into a, b and c subtypes depending on the severity of the villous atrophy, where c is total villous atrophy. In this slide are areas where there are no evidence of villi, so it’s Marsh 3c. ''The Marsh classification originally had a Marsh 4 as well, which included hypoplasia of the small bowel architecture, but the original classification has been revised to only go from 1 – 3.'' The number of intestinal crypts (of Lieberkühn) is normally low in the duodenum, however here can we see that crypts are plenty.