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7. Parenchymal degeneration in kidney: Difference between revisions
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(Created page with "'''Staining''': HE '''Organ''': Kidney '''Description''': We can see “cloudy swelling”, the tubular cells are swelled and no longer has the normal morphology. This degeneration can be seen in the whole slide. The swelling comes from transparent vacuoles inside the cytoplasm. '''Diagnosis''': Parenchymal degeneration '''Theory''': The morphological change called cloudy swelling is actually ''hydropic'' or ''vacuolar'' degeneration. Hydropic degeneration is the f...") |
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'''Staining''': HE | [[File:Parenchymal degeneration of kidney overview.jpg|thumb|Overview]]'''Staining''': HE | ||
'''Organ''': Kidney | '''Organ''': Kidney | ||
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A cause of hydropic degeneration in the kidney can be cardiac failure. When the heart fails to maintain the cardiac output, all organs will be ''hypoperfused'', which initiates the usual cell injury changes (hypoxia, glycolysis, less ATP.) If the cell injury is maintained for a long time, or the lack of ATP becomes too severe, the cell will die by necrosis. | A cause of hydropic degeneration in the kidney can be cardiac failure. When the heart fails to maintain the cardiac output, all organs will be ''hypoperfused'', which initiates the usual cell injury changes (hypoxia, glycolysis, less ATP.) If the cell injury is maintained for a long time, or the lack of ATP becomes too severe, the cell will die by necrosis. | ||
[[File:Parenchymal degeneration of kidney cloudy swelling.jpg|thumb|On this figure you can see what cloudy swelling looks like.]] | |||
[[File:Parenchymal degeneration of kidney cloudy swelling.jpg | |||
[[Category:Pathology 1 - Histopathology slides]] | [[Category:Pathology 1 - Histopathology slides]] | ||