5,045
edits
3. Necrosis. Ultrastructural, light microscopical and gross changes: Difference between revisions
3. Necrosis. Ultrastructural, light microscopical and gross changes (view source)
Revision as of 10:10, 6 May 2022
, 6 May 2022no edit summary
(Created page with "Necrosis is the “catastrophic”, “dirty” (as opposed to clean apoptosis) type of cell death, the type that happens when something goes very wrong. That “something” can be many things (see causes of cell injury in topic 2). When a cellular injury is so severe that the cell cannot recover from it, we say that the injury has reached the point of no return, and that is when the cell undergoes necrosis. We often talk about necrosis as a response to hypoxia, often b...") |
No edit summary |
||
| Line 9: | Line 9: | ||
== Light microscopy changes == | == Light microscopy changes == | ||
[[File:The light-microscopical changes in necrosis..png|thumb|The light-microscopical changes in necrosis. Taken fron a kidney infarction. «I» shows the infarcted area, while «N» shows the normal tissue. Notice that the infarcted tissue is more eosinophilic, has less structure and has fewer nuclei.]] | |||
Necrotic cells have certain characteristics when viewed in a light microscope. | Necrotic cells have certain characteristics when viewed in a light microscope. | ||
| Line 17: | Line 18: | ||
** Karyorrhexis, the fragmentation of the remaining nucleus into invisible bits. | ** Karyorrhexis, the fragmentation of the remaining nucleus into invisible bits. | ||
* Loss of tissue structure | * Loss of tissue structure | ||
[[Category:Pathology 1 - Theoretical exam topics]] | [[Category:Pathology 1 - Theoretical exam topics]] | ||