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38. Antineoplastic drugs: Cytotoxic drugs: Difference between revisions
38. Antineoplastic drugs: Cytotoxic drugs (view source)
Revision as of 11:06, 18 April 2023
, 18 April 2023Created page with "Cytotoxic drugs inhibit division of tumor cells and induce their apoptosis, usually by damaging DNA or interfering with mitosis. They’re more effective against rapidly dividing tumor cells. Alkylating agents like cyclophosphamide alkylates and damages DNA. Antimetabolites like methotrexate are structurally similar to important metabolites and can be incorporated into DNA or damage DNA in other ways. Cytotoxic antibiotics like doxorubicin inhibit topoisomerase II and d..."
(Created page with "Cytotoxic drugs inhibit division of tumor cells and induce their apoptosis, usually by damaging DNA or interfering with mitosis. They’re more effective against rapidly dividing tumor cells. Alkylating agents like cyclophosphamide alkylates and damages DNA. Antimetabolites like methotrexate are structurally similar to important metabolites and can be incorporated into DNA or damage DNA in other ways. Cytotoxic antibiotics like doxorubicin inhibit topoisomerase II and d...") |
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