Nikolas
Created page with "<section begin="orthopaedics" />* Epidemiology ** Children, adolescents ** Boys > girls * Clinical features ** Can occur in any bone *** Most often in diaphysis of long bones ** Highly malignant ** Night pain ** B symptoms * Diagnosis ** Resembles osteomyelitis on x-ray, MRI and histology ** Immunohistological staining or PCR helps to differentiate * Treatment ** Neoadjuvant polychemo + limb-sparing surgery + adjuvant polychemo ** Radiation may also be used <section end=..."