A1. Definition and emergency treatment of shock

Circulatory shock, often called just shock is a hemodynamic disturbance which leads to inadequate oxygen supply to organs and tissues of the body. The ensuing tissue hypoxia causes metabolic disorder in the tissues leading to temporary or permanent disturbance of function, and in severe cases to necrosis.

It’s a life-threatening condition which can develop as a complication of disease, procedure, or trauma. The most common form is septic shock, followed by cardiogenic and hypovolaemic. Shock is an emergent state which requires emergency management. Treatment must be both supportive and, subsequently, targeted against the underlying cause.

Etiology and types

Cardiogenic Shock

Cardiogenic shock is the most severe form of acute decompensated heart failure and occurs due to cardiac dysfunction which leads to inadequate tissue perfusion despite adequate intravascular volume.

  • Intrinsic (heart muscle insufficiency)
    • MI, low contractility
    • Severe tachy-or bradycardia, arrhythmias
    • Valve dysfunctions (aortic stenosis, ++)
  • Extrinsic
    • Tear in septum/ventricle wall

Distributive Shock

Distributive shock refers to shock due to vasodilatation of peripheral blood vessels, i.e. blood volume is normal but vascular volume is enlarged. CO increased but SVR decreased.

Hypovolaemic shock

Hypovolaemic shock refers to any shock due to insufficient circulating blood volume.

Obstructive shock

Obstructive shock is shock due to obstruction of blood flow outside the heart.

Clinical features

Shock is characterised by features of decreased end-organ perfusion, including:

There may also be symptoms specific to the type and underlying cause of the shock. For example, hypovolaemic shock may cause decreased skin turgor and dry mucous membranes. Cardiogenic and obstructive shock may cause distended neck veins. Septic shock may present with flushed, warm skin in the early stages.

Diagnosis and evaluation

The diagnosis of shock is clinical and depends on the presence of typical clinical features. Metabolic acidosis, especially lactic acidosis, is often present. Can see features of end-organ dysfunction or the underlying cause.

Treatment

Shock is an emergent state which requires emergency management. Treatment must be both supportive and, subsequently, targeted against the underlying cause. This involves:

A fluid challenge refers to giving a small amount of IV fluid and see whether the haemodynamic parameters improve, to assess whether the patient is fluid responsive (requires fluids) or not. A passive leg raise test can be used instead of a fluid challenge. In this test the patient’s legs are passively raised for one minute. This increases preload and will improve the haemodynamic parameters if the patient is fluid responsive.

Subsequent management depends on the type of shock and cause:

Complications