40. Paget disease of the breast
Staining: HE
Organ: Nipple
Description:
The squamous cells of the epidermis are replaced by tumor cells showing significant atypia.
The actual tumor or DCIS is not visible on this slide.
Diagnosis: Paget disease of the breast
Causes:
- Cancer cells invading the epidermis of the nipple
Theory:
Paget disease of the breast can occur both in DCIS and in invasive carcinoma. It can look like eczema.