36. Carcinoma of the breast

Organ: Breast

Description: The tumor has no capsule, isn’t well-circumscribed and doesn’t have a clear, expansile border. The tumor invades the skin and surrounding parenchyme and fat tissue.

Diagnosis: Carcinoma of the breast

Risk factors:

Genetic predisposition (BRCA)
Increases after 30 years
Positive family history
Nulliparity

Theory:

The most important in patho 1 is to know the characteristics of malignant tumors compared to benign ones, i.e.:

Not encapsulated
Poorly circumscribed
No expansile border
Can metastasize

A special feature of breast carcinoma is that it causes retraction of the skin. The tumor is firm and palpable due to the desmoplastic neostroma.